River sizing?

$1/3 6handed
Hero is the effective stack $550
Hero in HJ AcQs
Pre-flop: Villain (UTG) $11, hero HJ 3-bets to $35,
Pertinent dynamics: Villain is opening very wide. I saw him opening J4o for $23, 74s. I have been 3-betting him often and he has not 4-bet me.
Flop: Qc6h3d (Pot: $73-$8 drop= $65)

Action: villain leads into me $55. Hero calls

Turn: Ks (Pot $175)

Action: Villain $110, hero calls

River: Qd (Pot: $395)

Action: Villain checks, Hero jams remaining $350.

Would you exploitatively size down on this river?