88 facing 3 bets on 643 board, 1/3 Live

Villain 1 = utg with ~100bb
Villain 2 = utg+1 with ~200bb
Villain 3 = c/o with ~80bb
Hero = button with ~200bb

Villains 1 & 2 are very loose and frequently raise or call raises pf, on flop, etc
Villain 3 has decent knowledge of the game. He makes some loose calls but he definitely has awareness.

PF action: villain 1 open raises to $25 (not terribly abnormal for him). Villain 2 calls (also pretty standard). Villain 3 also calls. Hero calls (probably a mistake but my question is really about the flop).

Flop is 643 rainbow. Villain 1 bets $75, villain 2 calls, villain takes a little time then calls. This concerned me. While I felt 88 is good, I was a bit worried that villain 3 flopped a set and was milking them. I was also fearing 99+ because villain 2 often just flatted with those hands.

Anyway, what's hero's best play here? My thought process was "I'm good, so raise," but then I started to think I was up against a better hand (two pair, set, 99+). I honestly had no idea where I stood after tanking.