I recognize that this is a great set-up for a 4bet, but when expanding your 4bet range against these types of opponents, you should use a linear range. So you can 4bet for value with a wider range of hands like AQo, AJs/KQs, and TT/99. 4bet with Ace-Wheel suited can be good against a player who is 3betting a wide range and will fold appropriately with hands like AJo that dominate you. I don't think you are in that situation here though.
Post-flop I think you played this hand reasonably. River seems like a spot that would be pretty seriously underbluffed: 4bet pot, Ace high board, Triple broadway board, large sizing relative to the stakes of the game. I would never call here. Maybe you are thinking of turning your hand into a bluff? When he bets $250 on the river I think he is repping a straight or better, so I don't think I like it. Maybe he bet/folds two pair though....
