Should I go broke with Bottom Set?

Limping along with pocket 2s is fine for set-mining, especially with deep stacks.

Your re-raise looks fine to protect your set from draws and get value. After the villain's shove, you face an expensive decision.

What are you losing to? Sets: 66 (possible), 88 (less likely due to preflop limp).

What are you beating?

Overpairs: Unlikely since they would probably raise preflop.
Two-pair hands: 86s, possibly played aggressively by weaker players.
Draws: Hands like 54s, 97s.

Pot odds:

You need to call ~195 BB more to win ~465 BB total.
You need around 42% equity to call profitably.

Given the unknown nature of the opponent and the potential for overplayed draws, two pairs and Over Pairs calling here is reasonable but risky.

If you think Villain is fishy, their shove range is wider, making this a good call overall.

Judging by the limp, this guy is a fish and could easily be blasting with the normal fishy plan of "oh i limp AA and then reraise, im so smart", overpairs, two pairs and random top pairs and draws. Lets be generous and say you lose to 6 combos of sets, he has way more other combos that you beat in his range, both in terms of value and bluffs. I think you gotta call, unless you have some other info that this specific guy only puts his stack in with the nuts (and to a fish, a random overpair or two pair might as well be the nuts).

Yeah good to notice this guy is probably not a strong reg and there's always the spazz/ overplay factor. Here more overplay than spazz, but yeah you should probably get it in. If this guy is indeed a rec that limps very often I would consider iso-ing, not because I think 22 are super strong, but because I think it will be higher EV to play HU IP vs a rec (especially if he's passive) than invite all the other players behind into the pot. But this goes out the window if he's the type to limp-raise a lot

why are we playing 200bbs deep, this hurts my fragile brain..

also, if we can discount sets, it's an ezpz call but i would be hesitant at stakes above micros playing anything less than a whale to pay off villain 200bbs deep with bottom set. one thing i would say is that, on a board this dry, villain may not play this aggressively with top set, unless he puts you on exactly bottom set or 2p. he is more likely to call and play future streets which is what i think weights him more towards 2p or some egregiously overplayed overpair, but ya never know!

also iso pre so we have more of a range advtg post and room to navigate otf, esp when ip as we are